KLO Garcinia Extract - ComeMerry

10 x 10 capsules
Contents: Garcinia 450 mg

€ 16.00

Category: Health supplement Label: Health Food Off label Claims: appetite suppressant bone and joint strengthener relieves constipation improves digestive disorders fights obesity and helps to reduce weight, rheumatism, scurvy, rich in vitamin C

Dosage: 2 capsules three times e a day 30 minutes before meals

Herbal One Garcinia Extract

100 capsules
Contents:
Garcinia 500 mg 84.75 % HCA
€ 5.20

Category: Health supplement Label: Health Food Off label Claims: appetite suppressant bone and joint strengthener relieves constipation improves digestive disorders fights obesity and helps to reduce weight, rheumatism, scurvy, rich in vitamin C,

Dosage: 2 capsules twice a day 30 minutes before a meal

 

PN Garcinia Extract

100 capsules
Contents:
Garcinia 500 mg 84.75 % HCA
€ 5.90

Category: Health supplement Label: Health Food Off label Claims: appetite suppressant bone and joint strengthener relieves constipation improves digestive disorders fights obesity and helps to reduce weight, rheumatism, scurvy, rich in vitamin C,

Dosage: 2-3 capsules three times a day 30 minutes before a meal

 

GEo Herbal Pathumthani Garcinia atroviridis Tea
Garcinia atroviridis 100%, dried
Contents: 30 g

€ 1.75

Place one tea bag into a glass with steaming hot water and let steep. Use the back of a teaspoon to gently squeeze the tea bag against the glass so as to extract the active ingredients of the herb.

Drink two glasses a day, one in the morning and one in the evening.

Garcinia
   Antimicrobial, antioxidant, antitumour-promoting and cytotoxic activities of
different

plant part extracts of Garcinia Griff, ex T. Anders.

Garcinia, with its distinctly sour sweet taste, has been used for centuries in South East Asia to make meals more filling.
* The active constituent in garcinia is called hydroxycitric acid or HCA and is gaining a reputation for assisting weight loss through appetite suppression and by reducing the body’s ability to form adipose(fatty) tissue during times of overeating.

The mechanism for garcinia’s weight loss ability is still not fully understood; but is believed to be through inhibiting the body’s ability to convert carbohydrates to fats. This leads to an increase in glycogen in the liver, which sends a message to the brain indicating satiety, and in turn reduces appetite.

In recent years studies are focusing on the most effective form of HCA to take for maximum therapeutic benefit. What is significant is that a recent Japanese study, using an animal model, indicated that during exercise the regular use of HCA promotes fat burning and spares carbohydrate utilization at rest and during exercise. Giving garcinia an indication for endurance exercise.
* Garcinia has also been historically used to treat gastric ulcers. A 2002 study indicates this herb works primarily through the action of one of these plant’s constituents, garcinol. Garcinol is known to lower acidity in the stomach and protects the gastric mucosa.
* The rind of Garcinia is also astringent, which is why it was also historically used in the treatment of diarrhoea and dysentery as well as having the added benefit in the treatment of gastric and duodenal ulcers.
* The ability for Garcinia’s component, HCA, to reduce blood lipid levels and lower blood cholesterol is another feature of this amazing natural medicine.
* More recently, it has been proposed that Garcinia has a hepato protective ability against external toxins, such as alcohol. A recent study showed that Garcinia prevented liver cells from becoming fibrotic and stopped cell damage caused by high blood lipid levels.

Mechanism Of Action Of Garcinia:

1.              Animal studies indicate its action is mediated by two pathways. HCA works by blocking lipogenesis or conversion of starches and sugars (excess of carbohydrates) into fat that is stored and increases our weight.

2.         This herbal supplement promotes the oxidation of lipids and spares carbohydrates. This action will result in lower blood levels of cholesterol and lipid i.e. a better lipid profile.

3.         The glucose or its stored form glycogen is promoted. As excess of glucose is spared from conversion to fat, this excess glucose is mediated by gluconeogenesis pathway to form glycogen.

4.         Glycogen signals the brain satiety center that sufficient food has been taken. So glycogen production with this herb further suppresses appetite.

5.         Another of its action is on Central Nervous system. It raises the levels of Serotonin like brain neurotransmitters that has role in regulation of appetite.

6.         This herb promotes thermogenesis process i.e. body's production of heat. This burns more calories and excess of stored fat.

Other Common Herbs For Weight Loss:

Some other herbs like St. John's wort, Chromium and 5 HTP are used with Garcinia for helping the overweight persons.

Traditional Uses of Garcinia:

Clinically approved uses of

Garcinia

Garcinia for Weight Loss:

In a study involving 60 obese men and women, the group is given G. cambogia for  eight weeks. And HCA was found to help people lose weight in comparison to placebo group who took dummy supplement.

One study on male Zucker obese rats showed the effectiveness of this herb for suppressing body fat accumulation. This study included the safety at high dosage with histopathological examination. The dose at 389 mg per kg of body weight per day (Too much than the normal dosage) was found safe and without causing toxic effects on testicles. This study suggested that G. cambogia extract inhibits the accumulation of lipids in fat cells in adipose tissue (Fat droplet size reduced from 30-40 microns to 10-20 microns).

Another study from Molecular Cell Biochemistry proved again in a 90 daystudy its efficacy in overweight management. The 60% HCA containing extract of Garcinia was found to promote fat oxidation, enhance serotonin release and its availability in brain, normalization of lipid profiles and reduction of serum leptin levels in overweight individuals. This study established its safety on many criteria as acue oral, dermal and eye irritation toxicities, mutation studies and mouse lymphoma tests.

HCA, the bio-available extract of Garcinia found safe for human use. This study was conducted to find out the effects of HCA on body weight and abdominal fat gene expression profile of Sprague-Dawley rats. The study concluded that HCA is found effective for restricting body weight gain in rats. However the plasma leptin levels were unaffected and abdominal fat leptin levels were lowered.

Another study found garcinia extract to be a potent inhibitor of ATP Citrate lyase, the cellular enzyme that hastens the break of citrate to Acetyl coenzyme A and oxalocitrate. This inhibition of the enzyme reduces the availability of Acetyl coenzyme A for fatty acid and lipid synthesis from spare carbohydrates like starches and sugars. This helps directly in restricting the weight gain and induces weight gain.

This study evaluated the effects of 3.3% garcinia extract on serum leptin and insulin. The findings suggested that this herbal supplement has leptin like activity and improved glucose metabolism.

Another reputed and controversial  study at Obesity Research Center at Columbia University, found no significant differences in estimated percentage of body fat mass loss between treatment groups, and the fraction of subject weight loss as fat was not influenced by treatment group. This study concluded that Garcinia failed to produce significant weight loss and fat mass loss beyond that observed with placebo.

Later some researchers pointed that the high fiber diet in this study might have interfered with absorption of HCA and monitoring HCA concentration in blood during the study period might resolve this controversy. Plus HCAworks best when we are taking a noraml fat diet and not starving ourselves with greatly reduced fat intake.

Protection from Gastric Ulcer with Garcinia:

Garcinia extract is found to increase the mucosal defensive mechanisms in stomach and thereby it is helpful as a protective agent against Gastric ulcers. The rats that were pretreated with this herbal supplement was found with decreased acidity and increased mucosal protective factors.

The G. cambogia extract was given in the dose of 1 gm/kg of body weight/day for 5 to 10 to 15 days to rats. This study tested the herbal extract effect with Indomethacin (20 mg/kg/day) induced ulcerogenic effect. This supplement reduced both the volume and acidity of gastric juice. Beside this effect on acid, the supplement showed promotion of defensive factors on gastric mucosa.