Phyllanthus amarus

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Phyllantus amarus

KLO Phyllanthus amarus 100 tablets

KLO Phyllanthus amarus Tablets - ÅÙ¡ãµéãº
100 compressed tablets

Ingredients: Phyllanthus amarus Schum.& Thonn Extract
€ 7.25

Category: Health Food
Label: Antipyretic
Off label Claims: for the treatment of fever, stomach pains, hepatitis, high blood pressure, and many more (see below)

Directions
1 to 2 tablets, 2 to 3 times a day

PN Phyllanthus amarus

PN Phyllanthus amarus Tablets - ÅÙ¡ãµéãº
100 capsules

Ingredients:Phyllanthus amarus Schum.& Thonn Extract
€ 6.55

Category: Health Food
Label: Antipyretic
Off label Claims: for the treatment of fever, stomach pains, hepatitis, high blood pressure, and many more (see below)

Directions
1 to 2 capsules, 3 times a day

Additional Health Benefits of Phyllanthus amarus:
 

  • lowers blood sugar levels

  • is a diuretic

  • may lower high blood pressure

  • lowers fever

  • stops diarrhea

  • may soothe back pain

Phyllanthus amarus in use against liver disease

Herbs to treat liver diseases
 
The popularity of herbal remedies is increasing and many patients with liver disease use them. Controlled treatment trials in diseases for which plant components claim to be effective are lacking, and most of the few studies so far published do not report the incidence of adverse effects. Nevertheless, a number of herbals show promising activity in the treatment of acute and chronic liver disease including silymarin as a potential antifibrotic, Phyllanthus amarus as an antiviral in chronic hepatitis B, Glycyrrhizin as a hepatoprotectant in chronic viral hepatitis, and a number of herbal combinations from China and Japan that deserve testing in appropriate studies [96,97]. Therefore, there is the necessity of premarketing drug-testing and pharmacovigilance for all herbals just as with any other drug. So far, the evidence supporting the use of herbals to treat chronic liver diseases is insufficient and herbs should not be recommended outside clinical trials.

Phyllanthus amarus has been highly valued in a number of countries "for its curative properties; in India the plant is often used by traditional medical practitioners for a variety of ailments, including asthma, bronchial infection" and diseases of -- and injury to -- the liver (as mentioned above), researchers L. Yeap Foo and Herbert Wong tell us in their 1992 article which appeared in the English journal, Phytochemistry [31 (2): 711-713].

According to an interesting passage from Dr. K.M. Nadkarni's Indian Materia Medica (1954), this botanical has been used for a wide array of indications:

The plant is considered [...] diuretic, astringent and cooling. A decoction of the plant is administered in jaundice [see below] [...] Whole plant is employed in some [...] genitourinary infections, [the] young tender shoots are [used in] chronic dysentery [and the] juice of the stem [is] mixed with oil in ophthalmia [eye treatments].

Used in China, Thailand, the Philippines, Cuba, Nigeria, Guam, East and West Africa, the Caribbean, and Latin America, this liver-protectant/detoxifier has been used, in recent years, most successfully in such conditions as jaundice and hepatitis B.

What's in it? Studies have already shown that the plant contains alkaloids, lignans, flavonoids [see Editor's Desk, p. 8, this issue], fatty acids, and vitamin C, just to name a few.

A brief overview on the importance of the liver

In Ayurvedic tradition, the psychosomatic view of the human being sees the body organs and systems as a unit, and the digestive tract and functions as being of highest importance to health.

The liver has a whole battery of functions, including: the formation and excretion of bile, which is necessary for digestion; keeping certain nutrients and fuel ready for the body to use, such as carbohydrates and lipids; manufacturing plasma proteins; activating specific vitamins; activating and deactivating body hormones; and detoxifying drug, chemical, and biological poisons, or toxins, that invade our body every day along with air, water, and food.

The beneficial specifics of Phyllanthus amarus on hepatitis B infections
 

Phyllanthus amarus Extract

>Phyllanthus amarus directly inhibits an enzyme DNA polymerase present in the Hepatitis B virus. This action of Phyllanthus amarus prevents replication of the Hepatitis B virus and thus decreases the viral load. Helps in clearing viral load in Hepatitis virus carriers too. Phyllanthus species has been used widely for a long period in India, China, and other countries.

The powdered leaves of this perennial herb were first used in clinical studies which looked at its usefulness in helping patients suffering from chronic liver damage due to extended hepatitis B virus infection.

The hepatitis B infection leads to the inability of the immune system to get rid of the virus from liver cells. Infection with the hepatitis B virus is verified by detecting levels of certain viral components in the blood. In this carrier state, a patient is continuously harboring and carrying the virus.

Following earlier studies showing beneficial effects in relation to supplementation with extracts of this plant and hepatitis B by S.P. Thyagarajan (Indian Journal of Medical Research 76:174, 1982) and P.S. Venkateswaran (Proceeding of the National Academy of Sciences of the U.S.A. 84:274, 1987), in 1990, S. Jayaram, and colleagues from the University of Madras, studied chronic carriers of HBV hepatitis. After 28 volunteers received Phyllanthus amarus in 250-mg doses for one to three months, 54.5 percent experienced loss of the carrier status.

In 1988, at Madras' Hospital for Children and the Government General Hospital, S.P. Thyagarajan, and colleagues, once again reported their results in treating carriers of hepatitis B with an extract of Phyllanthus amarus. For a one-month period, the treated patients were given 200 mg of the extract in capsule form, three times a day. Fifteen to 20 days following the end of treatment, 59 percent of the hepatitis B carriers (22 of 37) lost their carrier status, which essentially meant that they no longer carried the disease. Only one out of 23 (4 percent) dummy-pill "treated" control patients irregularly lost their carrier status.

Thyagarajan and Jayaram joined forces once again, in 1990, in a study which examined patients with acute viral hepatitis B. In this study, patients with acute viral hepatitis were given Phyllanthus amarus (250 mg, three times a day) for 30 days. The rate of "cure," or elimination of the virus, was 40 percent for those patients who received supplementation with this power botanical.

How does it do what it does?

One possibility is that Phyllanthus amarus may block the spread (proliferation) of the virus by directly blocking, or preventing, replication of the virus' genetic material.

Blood-pressure regulation

Hajime Ueno, and colleagues, at Japan's Medical and Pharmaceutical University, discussed Phyllanthus amarus (called niruri in their paper) and blood pressure control in a 1988 article which appeared in the Journal of Natural Products.

These researchers, who were working as part of collaborative study between the Japan International Agency and the Republic of Paraguay, found that a component in the botanical held back, or was inhibitory against, the action of angiotensis-converting enzymes (ACEs), which, by definition, implicates the shrub as an important role-player in blood-pressure regulation, as well.

 

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